Synthesis of polyhydroquinoline derivatives via a four‐component Hantzsch condensation catalyzed by tin dioxide nanoparticles, By Mehdi Hatami

Research

Title	Synthesis of polyhydroquinoline derivatives via a four‐component Hantzsch condensation catalyzed by tin dioxide nanoparticles
Type	Article
Keywords	Nano tin dioxide catalyst Hantzsch condensation Polyhydroquinoline 1,4‐Dihydropyridine
Researchers	Seyed mohammad vahdat، Fereshteh Chekin، Mehdi Hatami، Maryam Khavarpour، Saeed Baghery، Ziba Roshan-Kouhi

Abstract

Tin dioxide (SnO2) nanoparticles efficiently catalyzed unsymmetrical four‐component Hantzsch condensations of various aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate to form polyhydroquinoline derivatives in excellent yields. This novel method offers several advantages over the traditional method of synthesizing these compounds, including safety, mild conditions, short reaction times, high yields, and an easy workup.