In this study, nanocomposite membranes based on cellulose acetate (CA) and nanodiamond (ND) were prepared by applying phase inversion methods. In order to achieve efficient dispersion and more hydrophilic NDs, they were functionalized via heat treatment (ND-COOH). The prepared nanocomposite membranes were characterized by contact angle, tensile strength, and pure water flux (PWF). The obtained results showed that the nanocomposite membranes with 0.5 wt.% of raw and functionalized ND exhibited excellent hydrophilicity, tensile strength, and PWF.