This paper introduces an energy-efficient configuration approach for on-off-keying (OOK) modulation, which is employed in a power amplifier (PA). The presented power amplifier features a dynamic multi-mode design that allows for adjustable data rates and output power in various modes, making it highly suitable for biomedical applications. By tweaking the duty cycle of the input data, the PA achieves an adjustable data rate, generating return-to-zero (RZ) data for RZ-OOK modulation. This modulation method ensures a direct correlation between data rate and power consumption, empowering the transmission of diverse power levels within allocated power constraints. The RZ data is also used to reconfigure the output power. The PA is designed in 180 nm CMOS technology, supports data rates that vary from 0.3 Mb/s to 3 Mb/s, and provides output power levels from -23 dBm to 0 dBm. When adjusting data rates, power dissipation ranges from 0.099 mW to 0.99 mW at an output power of 0 dBm. Moreover, the PA draws between 0.07 mW and 0.99 mW over the tuning range of the output power at the maximum amount of data rate.
