Electrowetting on a dielectric (EWOD) mechanism has shown great potential to transport and manipulate capsulated samples inside a droplet. In this research, we have described the EWOD phenomenon on a printed-circuit-board (PCB) substrate by using numerical and simulational studies. The droplet motion has been numerically investigated by employing a finite element method simulation. The electrowetting mechanism has been investigated by solving the multiphysic coupled electrostatic and droplet physics. The threshold voltage is studied for the proposed system. Both the effective EWOD force and droplet velocity are increased linearly by increasing the applied electric field and the velocity of 0.2 mm/s has been achieved for 300 V electric potential.