Reza Saghafi

The low diameter of nanofibers, high specific surface, flexibility, desirable mechanical properties, and the porous nature of nanofibers, make such nanostructures as a suitable choice for many medical applications. Suture yarn as a biodegradable material is one of the mechanical methods for closing and healing of wounds. Suitable suture should have some characteristics such as making the least tissue reaction, antibacterial properties, non-sensitivity, non-carcinogenicity, low price, comfortable handling, proper tensile strength and suitable binding ability. In this paper, hybride nanofiberous yarn containing chitosan/poly (vinyl alcohole) (PVA/CS) with the blend ratio of (75:25) and poly lactic acid (PLA) were fabricated by electrospinning process. For this CS/PVA and PLA solutions were injected from two different syringes. These two different syringes had positive charge and the collector for assembling fibers had negative charge. In the composition of produced micro and nano fibrous yarn, both PLA and PVA/CS exist with the blend ratio 75:25. Fabricated yarns were assessed for their morphological, surface, mechanical characteristics. However, the hydrophilicity nature of produced mat was analyzed by reporting contact angle measurements. The SEM images exhibited porous and smooth fibers with parallel arrangement. The mechanical strength of produced yarn was about 79.26 Mpa. The presence of chitosan/PVA component in yarn composition changed the hydrophilic/hydrophobic balance. The results of this paper showed that these yarns are good candidate for application as wound sutures.