In this study, the sage seed gum (SSG) was electrospun as a polysaccharide polymer
blended with polyvinyl alcohol (PVA) to construct nanofibrous mats for antibacterial
applications. The rheological properties of the PVA/SSG solutions were investigated
before electrospinning. Oscillatory, shear, and steady shear tests demonstrated that the
PVA/SSG solutions had a viscous behavior, exhibiting a higher consistency coefficient (k)
and a lower flow behavior index (n) at the higher PVA incorporation levels. The
morphological studies by SEM images revealed that the PVA/SSG nanofibers were
produced without bead defects within the diameter range of 130–300 nm. The in vitro
degradation tests showed that the PVA/SSG nanofibers (at different SSG contents) were
degraded by approx. 60–70% of their initial weight after one day of the degradation test.
The antibacterial activity against Escherichia coli and Staphylococcus aureus microbial species
and biodegradation tests also verified that the produced nanofibers could be implemented
for antibacterial applications. The SSG polymer in the form of nanofibers can be,
therefore, used as a natural and low-cost polymer for special antibacterial applications
such as wound healing.