عنوان	In-vitro biological behavior of calcium phosphate coating applied on nanostructure surface of anodized Nitinol alloy
نوع پژوهش	مقاله چاپ شده
کلیدواژه‌ها	Nitinol,nanostructure,calciumphosphate,fibroblastcell
چکیده	In the present study, an anodizing process was used to modify the surface of Nitinol alloy. Then, the calcium phosphate (CaP) coating was applied on the modified surface of Nitinol via pulse electrodeposition method. The field emission scanning electron microscope (FE-SEM) images obtained from the anodized sample showed that the nanostructure features were created by anodizing on the Nitinol surface. The influence of two different electrolytes on the morphology, chemical composition and microstructure of the applied coatings was studied by scanning electron microscopy (SEM) images and the x-ray diffraction (XRD) analysis. The results of in-vitro tests revealed that the spherical shape particles of the bone-like apatite could be formed on the samples coated with CaP layer after 10 days exposure to simulated body fluid (SBF). Furthermore, the CaP coatings facilitated the proliferation of fibroblast cells after 4 days of culture. After 4 days the methyl thiazole tetrazodium (MTT) assay indicated that applying the CaP coatings increased proliferation, viability and density of cells.
پژوهشگران	لیلا فتح یونس نژند (نفر دوم)، جعفر خلیل علافی (نفر چهارم)، سید امید رضا شیخ الاسلامی (نفر اول)، محمدرضا اصمینان فر (نفر سوم)